Introduction to Zidolam N 300mg/150mg/200mg Tablet
Zidolam N 300mg/150mg/200mg Tablet contains the active ingredient Lamivudine + Nevirapine + Zidovudine. It is a combination of three antiretroviral medicines. Lamivudine and Zidovudine mainly belong to the class of medications called nucleoside/nucleotide reverse transcriptase inhibitors. Nevirapine belongs to the class of medication called non-nucleoside reverse transcriptase inhibitors. It is used to treat HIV-1 infection.
This tablet is not advised for patients with anemia (low red blood cells) or neutropenia (low white blood cells). Inform your doctor if you have any liver disease, including hepatitis B or C, kidney disease, or are overweight. The administration of this tablet is associated with hematologic toxicity (decrease in blood cells), muscle weakness, liver diseases and infection, and lactic acidosis (acid buildup due to problems in the body’s metabolism). This medication is not advised for children less than 35 kg. Lamivudine, Nevirapine, and zidovudine tablets may cause decreased fertility in females. Talk to your physician if you have any concerns about fertility.
Zidolam N 300mg/150mg/200mg Tablet is not recommended if you are allergic to this drug or any other active substance or if you are pregnant or breastfeeding women. Inform your physician if you have liver issues, hepatitis infection, kidney diseases, or undergoing dialysis. Tell your physician if you have any active skin conditions such as rash. This tablet can interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. It’s necessary to inform your doctor about all your medications, including prescription, over-the-counter, and herbal supplements, to ensure no potential interactions.
Therapeutic Effects of Zidolam N 300mg/150mg/200mg Tablet
Zidolam N 300mg/150mg/200mg Tablet is a combination of three antiretroviral medicines. Lamivudine and Zidovudine work by inhibiting the reverse transcriptase enzyme of HIV, restricting viral genome replication, and reducing the production of new infectious viral particles. It mainly interferes with reverse transcription and inhibits the spread of HIV. Nevirapine directly binds to reverse transcriptase (RT) and blocks RNA-dependent and DNA-dependent polymerase activities by disrupting the enzyme.
Interaction of Zidolam N 300mg/150mg/200mg Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications, including ganciclovir, interferon alfa, and ribavirin, may exacerbate the toxicity of zidovudine interaction with Zidolam N 300mg/150mg/200mg Tablet and reduce its effectiveness by causing undesirable side effects.
More Information about Zidolam N 300mg/150mg/200mg Tablet
- Store Zidolam N 300mg/150mg/200mg Tablet below 30°C
- Keep the medicine out of reach of children and pets
How to consume Zidolam N 300mg/150mg/200mg Tablet
Take the Zidolam N 300mg/150mg/200mg Tablet as advised by your physician. Swallow the tablets whole and intact. This tablet should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.
Safety Advices for Zidolam N 300mg/150mg/200mg Tablet
Pregnancy
Do not take Zidolam N 300mg/150mg/200mg Tablet if you are in your first trimester because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.
Breast Feeding
Breastfeeding is not recommended in patients taking Zidolam N 300mg/150mg/200mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Lungs
It is unknown whether Zidolam N 300mg/150mg/200mg Tablet is safe for patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.
Liver
Zidolam N 300mg/150mg/200mg Tablet should be cautiously used in patients with liver diseases. Dose adjustments are necessary. However, inform your physician of any liver diseases before initiating the therapy.
Alcohol
It is unknown whether consuming alcohol while taking Zidolam N 300mg/150mg/200mg Tablet is safe. Please speak with your physician.
Driving
It is unknown whether Zidolam N 300mg/150mg/200mg Tablet alters the ability to drive or operate heavy machinery. If you feel sleepy or dizzy, avoid driving and consult your doctor.
Side Effects of Zidolam N 300mg/150mg/200mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Lactic acidosis (breathing difficulties along with weakness in limbs, stomach pain, vomiting, and drowsiness)
- Severe skin reactions and rash (blisters, red or inflamed eyes, swelling of the face, mouth sores, joint aches, fever, tiredness)
- Liver problems (yellowing of skin, eyes, fever, tea-colored urine, light-colored stools, pain in right side of ribs, loss of appetite)
- Osteonecrosis (stiffness and pain in joints, difficulty moving)
- Symptoms of muscle weakness or infection
- Loss of fat from legs, face, and arms
Common
- Nausea
- Diarrhea
- Headache, dizziness
- Cough
- Difficulty sleeping