Introduction to Nitib 140mg Capsule
Nitib 140mg capsule consists of the active ingredient Ibrutinib. It is indicated to treat blood cancers such as mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (CLL), Waldenstrom’s macroglobulinemia, and Marginal zone lymphoma (MZL). These are cancers of the white blood cells called lymphocytes that are part of the immune system. They differ from each other by the location where cancer occurs, type of lymphocytes affected, and certain other factors
Nitib 140mg capsule is also used to treat chronic graft versus host disease (cGvHD) after the failure of systemic therapy. During allogeneic stem cell transplantation, the patient receives stem cells from the donor. GvHD occurs when donor cells attack the patient’s cells as foreign. Before taking Nitib 140mg Capsule, you need to talk with your physician if you have bleeding problems, infection, liver problems, heart problems, or intolerance to some sugars. This medication is not recommended for adolescents and children.
It is vital to let the physician know if you have recently had or are about to have any surgical procedure. Your physician may stop Nitib 140mg capsule for any planned surgical or medical procedure. Use effective birth control during the treatment and for at least one month after the final dose. Avoid having grapefruit or oranges in any form during this treatment; they may raise the amount of drug in the blood. Drink plenty of fluid to prevent dehydration. Inform your physician if you have diarrhea that does not go away.
Therapeutic Effects of Nitib 140mg Capsule
The mechanism of action of Nitib 140mg involves blocking a specific protein called Bruton’s tyrosine kinase (BTK) which plays a key role in the survival and growth of cancer cells. By inhibiting BTK, Nitib 140mg prevents the cancer cells from receiving the signals they need to grow and divide, leading to their eventual death.
Interaction of Nitib 140mg Capsule with other drugs
Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interacting with Nitib 140mg , may reduce effectiveness by causing undesirable side effects.
More Information about Nitib 140mg Capsule
- Store the capsules in the original packaging at room temperature (20-25°C).
How to consume Nitib 140mg Capsule
Consume this medicine at the same time each day. While taking Nitib 140mg , do not consume grapefruit or orange in any form during the treatment. Drink plenty of fluid to prevent dehydration.
Safety Advices for Nitib 140mg Capsule
Pregnancy
This medicine can harm the unborn baby. Do not take Nitib 140mg Capsule unless your physician instructs you to take it. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Breast Feeding
Do not breastfeed while you are under Nitib 140mg capsule and for at least one week after the last dose. Consult your physician for risks and benefits.
Lungs
Nitib 140mg capsule may cause interstitial lung disease. So if you have any respiratory disorder, inform your doctor before starting the treatment.
Liver
Inform your physician before starting this treatment if you have liver problems, including hepatitis B infection. Nitib 140mg capsule could cause the reactivation of the hepatitis B virus, which makes the condition fatal.
Alcohol
It is unknown whether it is safe to consume alcohol with the Nitib 140mg capsule. Please consult your doctor.
Driving
Nitib 140mg capsule may cause dizziness or tiredness. Avoid driving or operating machines if you feel dizzy or tired.
Side Effects of Nitib 140mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Bleeding problems
- Infections
- Decrease in blood cell counts
- Heart problems
- High BP
- Secondary cancer
- Tumor lysis syndrome
- Severe allergic reactions
Common
- Nausea, vomiting, diarrhea
- Tiredness
- Muscle and bone pain
- Rash and bruising
- Mouth sores
- Pneumonia
- Fever, chills
- Breathlessness
- Constipation
- Dizziness
- Body pain
- Swollen ankles and feet
- Increased creatinine levels in blood
- Heavier periods and blood in urine
- Blurred vision
- Weakness and numbness