Introduction to Mistaurin 25mg Capsule
Mistaurin 25mg capsule contains the active substance midostaurin. It is an anti-cancer medicine that belongs to the class of medications called tyrosine kinase inhibitors. It is combined with other chemotherapy medications to treat acute myeloid leukemia (AML) in adults with a defect in a gene called FLT3. Acute myeloid leukemia is a form of cancer that starts in certain WBC called myeloid cells in which the body overproduces these cells abnormally. The medicine is also used in adults to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).
Do not take Mistaurin 25mg capsule if you are allergic to Midostaurin or any other ingredients of this medicine. Inform your healthcare professional if you have any symptoms of an infection, heart disorder, lung problems, or problems with breathing. If you experience any of these symptoms, such as fever, sore throat, mouth ulcers, cough with or without mucous, chest pain, difficulty breathing, or swelling in the body parts after taking the medicine, immediately report it to your doctor.
This medicine is not recommended for children and adolescents below 18 years of age. Inform your physician if you are pregnant, breastfeeding, or planning for pregnancy before initiating the therapy. Mistaurin 25mg capsule may reduce fertility in men and women; discuss this with your doctor before starting the therapy. This medicine’s most common side effects are fever with reduced blood cell counts, nausea, vomiting, headache, musculoskeletal pain, increased blood glucose levels, and respiratory tract infection.
Therapeutic Effects of Mistaurin 25mg Capsule
Mistaurin 25mg capsule is a kinase inhibitor that potently inhibits multiple receptor tyrosine kinases. It blocks the action of the kinases in the abnormal cells that express FLT3 mutant genes and stops their division and growth.
Interaction of Mistaurin 25mg Capsule with other drugs
Inform your healthcare provider about all the medicines you are taking, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Mistaurin 25mg capsule and reduce its effectiveness by causing undesirable side effects.
More Information about Mistaurin 25mg Capsule
- Store Mistaurin 25mg capsule at room temperature (25°C)
- keep the capsule away from the reach of children and pets.
- If you miss a dosage, take it as soon as you remember. If it is almost time for the next dose, skip the missing dose.
- Do not take a double dose to compensate for a missed dose.
How to consume Mistaurin 25mg Capsule
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the Mistaurin 25mg capsule as prescribed by your doctor. Do not open, break, crush, or chew the capsules. Swallow the capsule whole with a glass of water. Take the capsules with food at the same time each day.
Safety Advices for Mistaurin 25mg Capsule
Pregnancy
Mistaurin 25mg capsule is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using effective contraception during the treatment and for at least 4 months after your last dose is necessary.
Breast Feeding
Breastfeeding is not recommended in patients taking Mistaurin 25mg capsule because the medicine passes into the breast milk in small amounts and may harm the baby.
Lungs
It is unknown whether Mistaurin 25mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Mistaurin 25mg capsule should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your physician if you have liver problems before initiating the therapy.
Alcohol
It is unsafe to consume alcohol when taking Mistaurin 25mg capsule because it may cause alcohol-related problems, epilepsy, or liver problems.
Driving
Driving vehicles or operating machinery after taking Mistaurin 25mg capsule is unsafe as you may develop dizziness and vertigo.
Side Effects of Mistaurin 25mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Swelling in the lower limbs
- Skin rash
- Increased blood sugar levels
- Abdominal pain
- Constipation, diarrhea
- Nausea, vomiting
- Musculoskeletal pain
- Headache
- Bleeding from nose
- Upper respiratory infection
- Tiredness
- Fever
Serious
- Heart failure
- GI bleeding
- Fever with decreased blood cell counts
- Hypersensitivity reactions
- Kidney problems
- Pneumonia
- Blood infection