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Mexate 15mg Tablet
Methotrexate
Uses of Mexate 15mg Tablet
- To treat certain types of cancers
- To treat severe psoriasis
- To treat rheumatoid arthritis
Introduction to Mexate 15mg Tablet
Mexate 15mg tablet contains the active substance Methotrexate. It is an anti-metabolite and immunosuppressant drug. It treats certain types of cancer, such as acute lymphocytic leukemia (ALL), meningeal leukemia, non-hodgkin’s lymphoma, soft tissue and bone sarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer in adults. It is also used to treat severe psoriasis in adults (a skin disease in which red, scaly patches form on some body areas). It is also indicated to treat rheumatoid arthritis (a disease of the joints) in adults.
Do not use Mexate 15mg tablet if you are allergic to methotrexate or any of the other ingredients of this medicine. Do not take this medicine if you have kidney or liver problems, blood disorders, weakened immune system, pregnant, or breastfeeding. Inform your physician immediately if you experience any symptoms of spitting and coughing up blood, general muscle weakness, vision disturbance, changes in thinking, memory, and orientation problems. This medicine may impair fertility. Avoid getting pregnant during the treatment and for six months after the last dose.
Tell your doctor if you have a stomach ulcer, active infection, or mild kidney problems and about any recent vaccinations before starting the treatment. Mexate 15mg tablet can cause serious side effects even with low doses; hence, regular follow-ups and routine laboratory tests will be necessary as a precaution. Do not use this medicine if you are pregnant, breastfeeding, or planning to get pregnant.
Therapeutic Effects of Mexate 15mg Tablet
Mexate 15mg tablet inhibits dihydrofolic acid reductase. Therefore, this medicine interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow and spread. In treating rheumatoid arthritis, this medicine is thought to stop or reduce inflammation in the joints by altering the body’s defense mechanism in the immune system.
Interaction of Mexate 15mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, vaccines, nutritional or vitamin supplements, and herbal products. Certain medications interact with methotrexate and reduce their effectiveness by causing undesirable side effects.
More Information about Mexate 15mg Tablet
- Do not store above 25°C
- Do not freeze
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose.
How to consume Mexate 15mg Tablet
Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this medicine. Do not chew, crush or dissolve the tablets. The score line is only there to help you break the tablet if you have difficulty swallowing it whole. Swallow the tablets whole with water.
Safety Advices for Mexate 15mg Tablet
Pregnancy
Do not use Mexate 15mg tablet during pregnancy because it can cause birth defects. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for six months after the last dose.
Breast Feeding
Breastfeeding is not recommended in patients taking Mexate 15mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Lungs
Mexate 15mg tablet should be cautiously used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Mexate 15mg tablet is contraindicated in patients with acute liver failure. Dose adjustments are necessary if you have liver problems. Inform your physician if you have any liver disease before initiating the therapy.
Alcohol
It is unsafe to drink alcohol while you take Mexate 15mg tablet because it may cause damage to your liver.
Driving
Mexate 15mg tablet may make you feel drowsy, dizzy, loss of co-ordination or can give blurred vision. Do not drive or operate heavy machinery if you experience any of these side effects.
Side Effects of Mexate 15mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Hairloss
- Photosensitivity
- Rash
- Diarrhea, Nausea and Vomiting
- Decreased WBC and platelet count
- Dizziness
- Tiredness, fever, and shivering
- Blurred vision
Serious
- Severe allergic reactions
- Spitting or coughing blood
- Chest pain
- Weakness on one side of the body
- Muscle weakness
Brand
Zydus Cadila
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