Introduction to Methostes 15mg Injection
Methostes 15mg Injection contains the active substance Methotrexate. It is an anti-metabolite and immunosuppressant drug. It treats certain types of cancer, such as acute lymphocytic leukemia (ALL), meningeal leukemia, non-hodgkin’s lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer in adults. It is also used to treat severe psoriasis in adults (a skin disease in which red, scaly patches form on some body areas). It is also indicated to treat rheumatoid arthritis in adults.
Do not use Methostes 15mg Injection if you are allergic to methotrexate or any of the other ingredients of this medicine. Do not take this medicine if you have kidney or liver problems, blood disorders, weakened immune system, pregnancy, or breastfeeding. Inform your physician immediately if you experience any symptoms of spitting and coughing up blood, general muscle weakness, vision disturbance, changes in thinking, memory, and orientation problems. This medicine may impair fertility. Avoid getting pregnant during the treatment and for six months after the last dose. Tell your doctor if you have a stomach ulcer, active infection, or mild kidney problems and about any recent vaccinations before starting the treatment. Methostes 15mg Injection can cause serious side effects even with low doses; hence, regular follow-ups and routine laboratory tests will be necessary as a precaution. Do not use this medicine if you are pregnant, breastfeeding, or planning to get pregnant.
Therapeutic Effects of Methostes 15mg Injection
Methostes 15mg Injection inhibits dihydrofolic acid reductase. Therefore, this medicine interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow, spread, and suppress the immune system in autoimmune diseases.
Interaction of Methostes 15mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications interact with Methostes 15mg Injection and reduce their effectiveness by causing undesirable side effects.
More Information about Methostes 15mg Injection
- Store the Methostes 15mg Injection below 25°C
- Do not freeze
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets.
How to consume Methostes 15mg Injection
Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this injection. Methostes 15mg Injection is injected into a vein (intravenously) or into muscle (intramuscularly). Do not self-administer this medicine.
Safety Advices for Methostes 15mg Injection
Pregnancy
Do not use Methostes 15mg Injection during pregnancy because it can cause birth defects. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for six months after the last dose.
Breast Feeding
Breastfeeding is not recommended in patients taking Methostes 15mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Lungs
Methostes 15mg Injection should be cautiously used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Methostes 15mg Injection is contraindicated in patients with acute liver failure. Dose adjustments are necessary if you have liver problems. Inform your physician if you have any liver disease before initiating the therapy.
Alcohol
It is unsafe to drink alcohol while you take Methostes 15mg Injection because it may cause damage to your liver.
Driving
Do not drive or operate heavy machinery if you experience any side effects such as dizziness, drowsiness, or blurred vision.
Side Effects of Methostes 15mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Hairloss
- Photosensitivity
- Rash
- Diarrhea, Nausea and Vomiting
- Decreased WBC and platelet count
- Dizziness
- Tiredness, fever, and shivering
- Blurred vision
Serious
- Severe allergic reactions
- Spitting or coughing blood
- Chest pain
- Weakness on one side of the body
- Muscle weakness