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Lorbriqua 25mg Tablet
Lorlatinib
Uses of Lorbriqua 25mg Tablet
- Metastatic non-small cell lung cancer (NSCLC)
Introduction to Lorbriqua 25mg Tablet
Lorbriqua 25mg tablet is a drug belonging to the class of tyrosine kinase inhibitors, containing the active ingredient Lorlatinib. It is used to treat metastatic non-small cell lung cancer (NSCLC). This is the most common type of lung cancer. Metastatic non-small cell lung cancer (NSCLC) is a type of lung cancer that has spread to other parts of the body, such as the bones, liver, brain, or other organs.
During the treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes, and kidney parameters to prevent serious complications. This medicine has the potential to cause liver damage. Also, it may cause decreased fertility in males and this could affect your ability to father a child. Talk to your healthcare provider if you have concerns about fertility.
Inform the doctor if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels, or hypertension before starting this treatment. Report to your doctor if you experience any hypersensitive reactions like itchy skin or rashes while taking this medicine. It is advised to avoid drinking grapefruit juice while taking this drug, as it may increase the level of the drug in the blood and cause side effects. This tablet contains lactose as an inactive ingredient in which the body is unable to digest lactose, a sugar found in milk and dairy products. It can cause symptoms such as bloating, and abdominal pain. If you have lactose intolerance, inform your doctor before starting this therapy.
Therapeutic Effects of Lorbriqua 25mg Tablet
It works by inhibiting the tyrosine kinases, thus preventing the activation of downstream signalling pathways that are involved in cell proliferation, survival, and differentiation. This leads to the inhibition of cancer cell growth and survival.
Interaction of Lorbriqua 25mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Lorbriqua 25mg tablet and reduce effectiveness by causing undesirable side effects.
More Information about Lorbriqua 25mg Tablet
- Store Lorbriqua 25mg tablet in the original package at a controlled room temperature (20°C to 25°C).
- Keep it out of reach from children.
How to consume Lorbriqua 25mg Tablet
Your doctor will decide the dose and duration of Lorbriqua 25mg tablet based on the disease condition and other factors. Take the tablet at the same time every day, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
Safety Advices for Lorbriqua 25mg Tablet
Pregnancy
Lorbriqua 25mg tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breast Feeding
It is not known if Lorbriqua 25mg tablets pass into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Lungs
Inform your doctor if you have any lung problems before taking Lorbriqua 25mg tablet. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Inform your doctor if you have any liver problems before taking Lorbriqua 25mg tablet. Regular monitoring of liver function tests is recommended.
Alcohol
Consuming alcohol may affect the effectiveness of Lorbriqua 25mg tablet. Stop consuming alcohol if you are taking this medicine.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking Lorbriqua 25mg tablets, it may cause dizziness and impair your concentration.
Side Effects of Lorbriqua 25mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Cough, chest pain, or worsening of breathing problems
- Feeling tired, faint, or losing consciousness
- Yellowing of the skin and eyes, vomiting, abdominal pain
- Confusion, memory loss, mood swings, difficulty speaking, seeing, or hearing things that are not real
Common
- Increase in cholesterol levels
- Swelling in hand or legs
- Double vision difficulty seeing
- Pain, numbness, or unusual sensations (burning or pin and needles) in arms and legs, difficulty walking
- Diarrhoea, constipation
- Headache
- Weight gain
- Joint pain, muscle pain
- Rash
- Anaemia
Brand
Pfizer LTD
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