Introduction to Janumet 50/500mg Tablet
Janumet 50/500mg Tablet contains an active component called the Sitagliptin and Metformin. It is a medication used in the management of type 2 diabetes. It helps to regulate blood sugar levels by targeting multiple aspects of glucose regulation. Unlike some other diabetes medications, it is not associated with significant weight gain and may even be associated with modest weight loss in some individuals. This can be a benefit for patients with type 2 diabetes who are overweight or obese. It is less likely to cause hypoglycemia (low blood sugar levels), particularly when used as directed. This can be beneficial for individuals who are at risk of experiencing hypoglycemic episodes. Some studies suggest that the use of this medication may have cardiovascular benefits, including reducing the risk of cardiovascular events, such as heart attacks or strokes, in patients with type 2 diabetes.
Individuals with a known allergy or hypersensitivity to tablet janumet 50/500mg or any other components of this medication should avoid using this medication. It should not be used in individuals with severe renal impairment (eGFR less than 30 mL/min/1.73 m²) or end-stage renal disease. Using it in such cases can increase the risk of developing lactic acidosis, a serious metabolic complication. Individuals with a history of metabolic acidosis, including diabetic ketoacidosis (DKA), should not use this medication. The use of this medication is not recommended in individuals with a history of heart failure, as certain studies have suggested an increased risk of cardiovascular events with this medication. Consult a healthcare provider before starting janumet 50mg/500mg tablet, especially if you are an older adult, as age-related changes in kidney and liver function may affect the dosage requirements. It is not recommended for use in children, as its safety and efficacy in paediatric populations have not been established.
Therapeutic Effects of Janumet 50/500mg Tablet
Janumet 50mg/500mg tablet works by combining its two active ingredients, which act synergistically. Sitagliptin enhances insulin release and reduces glucagon levels, while metformin decreases liver glucose production and enhances peripheral glucose uptake. Together, they help control blood sugar levels in individuals with type 2 diabetes.
Interaction of Janumet 50/500mg Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the janumet 50mg/500mg tablet, reducing effectiveness by causing undesirable side effects.
More Information about Janumet 50/500mg Tablet
- Store at room temperature, between 20°C to 25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Janumet 50/500mg Tablet
Janumet 50mg/500mg tablets can be administered orally.. Follow the prescribed dosage and any additional instructions provided by the healthcare professional for the safe and effective use of janumet 50mg/500mg tablet.
Safety Advices for Janumet 50/500mg Tablet
Pregnancy
Janumet 50mg/500mg tablets are not recommended during pregnancy. Discuss the potential risks and benefits with a healthcare provider before using it during pregnancy.
Breast Feeding
Janumet 50mg/500mg tablets may not be recommended for breastfeeding mothers. Consult a healthcare provider for guidance on using this medication while breastfeeding.
Lungs
Consult your healthcare provider if you have a history of lung conditions before using the janumet 50mg/500mg tablet.
Liver
If you have liver disorders, informing your healthcare provider before starting the janumet 50mg/500mg tablet is important.
Alcohol
It is not safe while taking janumet 50mg/500mg tablet, as alcohol can increase the risk of lactic acidosis.
Driving
Janumet 50mg/500mg tablets are generally not known to impair the ability to drive or operate machinery. However, individual responses may vary, especially in cases of hypoglycemia or other adverse effects. If you experience any symptoms, consult your healthcare provider.
Side Effects of Janumet 50/500mg Tablet
Janumet 50mg/500mg tablets cause some side effects like all medications, although not everyone will experience them.
Serious
- Lactic Acidosis
- Pancreatitis
- Hypoglycemia
Common
- Diarrhea
- Nausea
- Vomiting
- Gas
- Stomach upset or pain