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Emgrast M 500mcg Injection
Sargramostim
Uses of Emgrast M 500mcg Injection
- Bone Marrow Transplantation
- Neutropenia caused by chemotherapy
- Acute Radiation Syndrome
- Peripheral Progenitor Cell Transplantation
Introduction to Emgrast M 500mcg Injection
Emgrast M 500mcg Injection contains the active ingredient sargramostim. It is an antineoplastic drug that belongs to the category of medicines known as colony-stimulating factors. This medicine is used in the treatment of chemotherapy-induced neutropenia and bone marrow transplantation. It is also found to be useful in treating acute radiation syndrome (this can occur when an individual is exposed to high levels of ionizing radiation over a short period of time). In addition, this medicine is also used to treat peripheral progenitor cell transplantation (a medical procedure used to replace damaged or diseased blood cells).
This drug is contraindicated in patients with known hypersensitivity to any of its components. Also, it should not be used in patients with excessive leukemic myeloid blasts or in patients with known hypersensitivity to yeast-derived products, as this drug is produced in yeast cells. Additionally, caution should be taken in patients with underlying medical conditions such as congestive heart failure, pulmonary infiltrates or pulmonary edema, or renal insufficiency, as these conditions may be exacerbated during the therapy.
This medicine has been associated with the development of capillary leak syndrome, a rare disorder that can cause fluid and protein to leak out of blood vessels and into surrounding tissues. If you experience any symptoms like swelling, low blood pressure, or difficulty breathing. Consult your doctor immediately. It is recommended to avoid administering solutions containing benzyl alcohol, including this injection, which should not be given to neonates and low birth weight infants. This drug is not recommended during pregnancy as it causes harm to the unborn baby. Tell your healthcare provider before beginning this treatment if you are pregnant or planning to have a baby.
Therapeutic Effects of Emgrast M 500mcg Injection
Emgrast M 500mcg Injection binds to specific receptors on the surface of bone marrow cells, which stimulates the proliferation and differentiation of hematopoietic stem cells. These cells then mature into various types of blood cells, including granulocytes, monocytes, erythrocytes, and platelets. By stimulating the production of these blood cells, this drug can help to prevent or treat certain types of bone marrow failure.
Interaction of Emgrast M 500mcg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Emgrast M 500mcg Injection and reduce its effectiveness by causing undesirable side effects.
More Information about Emgrast M 500mcg Injection
- Store Emgrast M 500mcg Injection in the refrigerator (2°C to 8°C)
- Do not freeze
How to consume Emgrast M 500mcg Injection
Emgrast M 500mcg Injection should only be administered by a trained doctor or nurse experienced in giving chemotherapy. The medicine will be given as a subcutaneous (under the skin) injection, usually once daily. The injection should be given at the same time every day, preferably in the morning. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.
Safety Advices for Emgrast M 500mcg Injection
Pregnancy
Emgrast M 500mcg Injection is unsafe to administer in pregnant women because it may fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6.5 months after your last dose is necessary.
Breast Feeding
Breastfeeding is not recommended in patients taking Emgrast M 500mcg Injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
It is unknown whether Emgrast M 500mcg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Emgrast M 500mcg Injection should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary. Inform your physician if you have liver problems before initiating the therapy.
Alcohol
It is unsafe to consume alcohol with Emgrast M 500mcg injection. Please consult your doctor for more advice.
Driving
The alcohol present in Emgrast M 500mcg Injection may affect your ability to drive. Avoid driving if you feel unwell.
Side Effects of Emgrast M 500mcg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (rash, itching, swelling of lips, tongue, wheezing, dizziness, feeling faint, fast heartbeat, sweating)
- Fluid retention (swelling of feet or ankles, urinating less than usual, dizziness, sudden weight gain, swelling of the stomach, feeling fullness)
- Skin flushing along with troubled breathing
- Abnormal heart rhythm
- Too high white blood cell count
Common
- Fever
- Nausea, vomiting
- Mouth sores
- Hair loss
- Weight loss
- Lung problems
- Urinary tract problems
- Diarrhea
- Headache
- Rash
- Abdominal pain
- High blood pressure
- Decreased appetite
- Feeling unwell, lack of energy
Brand
Emcure
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