Cladrim 10mg Injection

Cladrim 10mg injection is an antineoplastic drug belonging to the category of medicines known as purine analogues, containing the active ingredient Cladribine. It is used in the treatment of Multiple Sclerosis (is a type of autoimmune disorder that affects the nervous system). It is also used to treat Hairy cell leukaemia (cancer of white blood cells).

This drug is contraindicated in patients with current malignancies, active chronic infections like tuberculosis or hepatitis, and for those with a history of hypersensitivity reactions. High doses of this drug have been associated with the irreversible neurologic toxicity (paraparesis/quadriparesis), acute nephrotoxicity, and severe bone marrow suppression resulting in neutropenia, anaemia and thrombocytopenia. Clinicians should also monitor patients frequently for signs and symptoms of neurological impairment, such as numbness or tingling in the arms or legs, weakness, or loss of bowel or bladder control. If these symptoms occur, urgent treatment is necessary to prevent further neurological damage. It is essential to inform your doctor if you have a history of any bleeding disorders, liver or kidney disease, or if you’re taking any other medications, including over-the-counter drugs, supplements, or herbal remedies.

Consult your doctor before using this medication if you are pregnant or plan to have a baby. This medicine is not recommended for pregnant women as it may cause fetal harm. Your health care practitioner will conduct a pregnancy test before you start treatment with this Injection. This medicine may cause birth defects if either partner uses it during conception or pregnancy. Male patients with female partners of reproductive potential should use effective birth control during the treatment and for 3 months after the last dose. Do not breastfeed during the treatment and for 10 days after the last dose. Avoid vaccination with live-attenuated or live vaccines during and after the treatment with this drug while the patient’s white blood cell counts are not within normal limits.