Actemra 400mg Injection

Actemra 400mg Injection

Tocilizumab

Uses of Actemra 400mg Injection

  • Rheumatoid arthritis
  • Giant cell arteritis (GCA)
  • Polyarticular Juvenile Idiopathic Arthritis (pJIA)
  • Systemic Juvenile Idiopathic Arthritis (sJIA)
  • Cytokine release syndrome

Introduction to Actemra 400mg Injection

Actemra 400mg injection contains an active component called tocilizumab. This medicine belongs to a group of monoclonal antibody (a protein made from specific immune cells). This is used in conditions such as moderate to severe active rheumatoid arthritis (RA) and who have inadequate response with other rheumatoid drugs, giant cell arteritis (disease in arteries), children with systemic juvenile idiopathic arthritis (sJIA), polyarticular juvenile idiopathic arthritis (pJIA) which result in the pain and swelling in one or more joints in children of 1 to 2 year and above.

Children with allergic reactions to ingredients and severe infections should consult their doctor before taking the medicine. Talk to your doctor immediately if you have any allergic reaction (difficulty with breathing, chest tightness rash, itching, hives, swelling lips, tongue, or face), infection (short- or long-term), tuberculosis, intestinal ulcers or diverticulitis (small bulging pouches developed in the digestive tract), liver disease, cancer, kidney function problems, and persistent headaches.

Inform your doctor if the Children have a history of macrophage activation syndrome (activation and uncontrolled proliferation of specific blood cells). The elderly are more likely to develop infections than the general population, so it is important to be cautious when treating them. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.

Therapeutic Effects of Actemra 400mg Injection

Actemra 400mg injection inhibits the function of a particular protein known as interleukin-6, which plays a role in the body’s inflammatory responses. By blocking this protein, it can help decrease inflammation within your body.


Interaction of Actemra 400mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with actemra 400mg injection and can cause undesirable side effects.


More Information about Actemra 400mg Injection

  • Protect from light and moisture
  • Store at 2°C – 8°C
  • Keep children away from the sight and reach of this medication.

How to consume Actemra 400mg Injection

Actemra 400mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.


Safety Advices for Actemra 400mg Injection

 

Pregnancy

Consult your healthcare provider if you plan to get pregnant. However, Actemra 400mg injection has not been given to expectant mothers, and it should only be used when the projected advantages outweigh any possible hazards to the fetus.

 

Breast Feeding

It is unknown whether actemra 400mg injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.

 

Lungs

It is unknown whether actemra 400mg injectionis safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

 

Liver

Inform your physician about any underlying liver disorders before taking actemra 400mg injection, as this medication should be used cautiously in liver disease patients.

 

Alcohol

It is unknown whether actemra 400mg injection is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.

 

Driving

Actemra 400mg injection may cause drowsiness in the patient while under medication. So, it is recommended to consult your doctor before handling vehicles and machinery.


Side Effects of Actemra 400mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

  • Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face)
  • Fever and chills
  • Mouth or skin blisters
  • Stomach ache

Common

  • Upper respiratory tract infections (cough, blocked nose, runny nose, sore throat and headache)
  • High blood fat (cholesterol) levels
  • Injection site reactions.
  • Lung infection (pneumonia)
  • Shingles (herpes zoster)
  • Cold sores (oral herpes simplex), blisters
  • Eye infection (conjunctivitis)
  • Headache, dizziness, high blood pressure
  • Mouth ulceration, stomach pain
  • Fluid retention (edema) in the lower legs, weight increase
  • Cough, shortness of breath
  • Low white blood cell counts (neutropenia, leucopenia)
  • Abnormal liver function tests (increased transaminases)
  • Increased bilirubin shown by blood tests
  • Low fibrinogen levels in the blood (a protein involved in blood clotting)

Brand

Cipla LTD

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